Rule for feminine · die
-ion → die · 2.2% (exception: das Stadion)
Nouns borrowed from French or Latin that end in -ion are almost always feminine and take die: die Region (region), die Situation (situation), die Union (union). The suffix covers 2.2% of frequent nouns, one of the most productive patterns for internationally-derived words. Watch out for das Stadion (stadium), though - it ends the same way but stays neuter, likely because it entered German as a technical term straight from Greek/Latin rather than through the usual -ion word-formation. Otherwise, the rule is solid and safe to trust.